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. 2020 Apr 15;11:557. doi: 10.3389/fimmu.2020.00557

Table 2.

Association between hsCRP, hsIL-6, and markers of tryptophan metabolism in the whole population.

TRP KYN/TRP 5-HT 5-HIAA IAA ICAld ILA IPA IS
hsCRP −0.397**** 0.190* −0.088 0.133 −0.332*** −0.078 −0.501**** −0.268** −0.339***
hsIL-6 −0.380**** 0.300** −0.158 0.068 −0.290** −0.108 −0.397**** −0.244** −0.304***

Multiple regression analyses controlling for gender, age and comorbidities (β coefficient). IAA, indole-3-acetic acid; ICAld, indole-3-carboxaldehyde; ILA, indole-3-lactic acid; IPA, indole-3-propionic acid; IS, indoxyl sulfate; KYN/TRP, kynurenine/tryptophan; 5-HT, serotonin; 5-HIAA, 5-hydroxyindole-3-acetic acid.

****

p < 0.0001,

***

p < 0.001,

**

p <0.01,

*

p < 0.05.