Figure 5.
Results of the behavioural identification in the resident intruder model of premenstrual dysphoric disorder (PMDD). (A) The representative photograph of control and PMDD-RIP rats in the composite aggressive test. (B) Composite aggressive score in the dioestrus I phase. (C) The representative trajectory diagram of control and PMDD-RIP rats in the OFT. (D) Total distance in the OFT. (E) Central area distance in the OFT. (F) Time in the central area in the OFT. (G) The representative trajectory diagram of control and PMDD-RIP rats in the EPM test. (H) Total distance in the EPM test. (I) Percentage of time in the open arm (OT%) in the EPM test. (J) Percentage of open-arm entry times (OE) in the EPM test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared with the control group. PMDD-RIP, premenstrual dysphoric disorder-resident intruder paradigm; OFT, open-field test; EPM, elevated plus maze; OE, open-arm entry times; OT, time in the open arm.