Table 1.

Description of bivalve species, sample sites, months, years and anthropogenic activities at each site, and histology and molecular analyses for Haplosporidia spp

Site # (Fig. 1)	Site	Anthropogenic activity	Month	Year	n	PCR+	Histology+	Sequencing
			Wild C. edule
13	Flaxfort	Rural/agriculture	March–June	2010 to 2011	900	1.7% (1/60)	0.11% (1/900)	1/Isolate221 (A#KY522823.1)
5	Dungarvana	Aquaculture & agriculture	April–August	2015	250	4% (10/250)	50% (10/20)	1/Isolate226 (A#KY522823.1)
1	Carlingforda	Aquaculture & shipping	April–August	2015	454	10.8% (49/454)	100% (20/20)	1/Isolate228 (A#KY522823.1)
	Total				1604	7.9% (60/764)	3.3% (31/940)
			Wild Mytilus spp.
1	Carlingforda	Aquaculture & shipping	April–August	2015	120	0/120	0/120
2	Annestown	Rural/agriculture	September	2017	30	0/30	0/30
3	Stradbally	Rural/agriculture	June	2017	30	0/30	0/30
4	Clonea	Rural/agriculture	September	2017	60	1.7% (1/60)	1.7% (1/60)	1/Isolate376 (A#KC8828762)
5	Dungarvana	Aquaculture & agriculture	September	2015 & 2017	276	0/276	0/276
6	Helvic Heada	Aquaculture & agriculture	June	2017	30	0/30	0/30
7	Ballyquinna	Rural/agriculture	June	2017	30	0/30	0/30
8	Whiting Bay	Rural/agriculture	July	2017	30	0/30	0/30
9	Ballymacodaa	Aquaculture & agriculture	June & November	2017	60	0/60	0/30
10	Roches point	Shipping		2017	60	0/60	0/60
11	Ringaskiddy	Urban & shipping	July & October	2017	60	3.3% (2/60)	3.3% (2/60)
12	Garrettstown	Rural/agriculture	May	2017	70	0/70	0/70
13	Flaxfort	Rural/agriculture	June	2017	60	0/60	0/60
14	Lough Hynea	MNR/rural/agriculture	May	2017	60	0/60	0/60
	Total				976	2.5% (3/120)	2.5% (3/120)
			Cultured C. gigas
5	Dungarvana	Aquaculture & agriculture	April–August	2015	180	0/180	0/60
1	Carlingforda	Aquaculture & shipping	April–August	2015	240	0/240	0/60
	Total				420

+ Positive detection.

A# denotes Genbank Accession Number exact match to.

^aSpecial Areas of Conservation (SAC) and Special Protected Areas (SPA) under the birds and habitats EU Directive.