Table 4.

Number of adverse drug reactions (ADRs) belonging to the System Organ Class (SOC) “Nervous system disorders,” “Psychiatric disorders,” and “Musculoskeletal and connective tissue disorders” and involving quinolones as suspected drugs recognized in the Campania spontaneous reporting system.

SOC - Reported Adverse Events Preferred term	Number (%)
Nervous system disorders Tremor Paraesthesia Headache Syncope Pre-syncope Formication Dizziness Ageusia Memory loss Anosmia Epilepsy Altered state of consciousness Metallic taste Paralysis Peripheral neuropathy Decreased level of consciousness Sudden fall Hypotonia Afasia Drowsiness Akathisia Burning sensation Cerebral Ischemia Balance disorder Hemiparesis	63 (47.7) 16 (25.4) 7 (11.1) 7 (11.1) 6 (9.5) 5 (7.9) 2 (3.2) 2 (3.2) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6) 1 (1.6)
Musculoskeletal and connective tissue disorders Myalgia Arthralgia Tendinitis Limb pain Tendon pain Musculoskeletal pain Rhabdomyolysis Arthromyalgia Hypercreatininemia Muscle rigidity Muscle tension Muscle inflammation Muscle weakness	45 (34.1) 9 (20.0) 9 (20.0) 8 (17.8) 5 (11.1) 4 (8.9) 3 (6.7) 1 (2.2) 1 (2.2) 1 (2.2) 1 (2.2) 1 (2.2) 1 (2.2) 1 (2.2)
Psychiatric disorders Insomnia Hallucination Confusional state Agitation Temporospatial disorientation Restlessness Irritability Acute psychosis Anxiety Drug abuse Dyssomnia Mood swing Auditory hallucination Mental disorder Psychotic disorder Panic attack	24 (18.2) 3 (12.5) 3 (12.5) 2 (8.3) 2 (8.3) 2 (8.3) 2 (8.3) 1 (4.2) 1 (4.2) 1 (4.2) 1 (4.2) 1 (4.2) 1 (4.2) 1 (4.2) 1 (4.2) 1 (4.2) 1 (4.2)
Total	132 (100.0)