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. 2020 Apr 15;12:86. doi: 10.3389/fnagi.2020.00086

FIGURE 3.

FIGURE 3

(A) Voxel-based statistical analysis of the diffusion tensor imaging parameter FA. (B,C) The change of white matter neural fiber (B) and fiber length in corpus callosum. The significant main effects of the phenotype are shown for the mean diffusivity. Results are displayed on an anatomical template with a visualization threshold of false discovery rate with P < 0.005 and a minimum cluster size of 20 voxels. The color scale indicates f-values, with yellow indicating a larger difference between the conditions investigated. Control-BCAS means that the FA value in BCAS rats is lower than in controls. BCAS-BCAO means that the FA value in BCAS rats is higher than in BCAO rats. The strongest effects according to the voxel-based analysis are displayed in the graphs. Data are expressed as the mean ± SD (n = 6/group). P < 0.05 compared with the control group; #P < 0.05 compared with the BCAS group. FA, fractional anisotropy; BCAS, bilateral common carotid artery stenosis; BCAO, bilateral common carotid artery occlusion; SD, standard deviation.