TABLE 2.
MSEL Expressive Language Raw Score – Change by TPH2 (rs11178997) (A/T) and TPH2 (rs4290270) (A/T) genotypes in the treatment group.
| Genotypea | Mean (95% Confidence Interval) | P-valueb | |
| TPH2 | AT (nc = 3) | 16.00 (4.90, 27.10) | 0.008 |
| (rs11178997) | TT (nc = 12) | 2.08 (−3.46, 7.63) | 0.432 |
| TPH2 | AA (nc = 6) | 12.0 (4.47, 19.53) | 0.004 |
| (rs4290270) | AT (nc = 8) | 0.5 (−6.02, 7.02) | 0.872 |
| TT (nc = 3) | −4.0 (−14.65, 6.65) | 0.434 | |
| Comparison | Difference in means (95% Confidence Interval) | P-valueb | |
| TPH2 (rs11178997) | AT – TT | 13.9 (1.51, 26.3) | 0.031 |
| TPH2 | AA – AT | 11.5 (−0.6593, 23.7) | 0.065 |
| (rs4290270) | AA – TT | 16.0 (0.0797, 31.9) | 0.049 |
| AT – TT | 4.5 (−10.7425, 19.7) | 0.725 | |
aGenotypes with fewer than three subjects with non-missing data were excluded. bP-values are adjusted for multiple pairwise comparisons using the Tukey HSD method. cN indicates the number of subjects.