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HDAC Enzyme Activity Data for Compound a9 and b8.
| Comp | IC50a (μM) | |
|---|---|---|
| HDAC1 | HDAC6 | |
| SAHA | 0.333 ± 0.01 | 0.475 ± 0.012 |
| a9 | 5.30 ± 1.31 | 8.90 ± 1.90 |
| b8 | 56.5 ± 2.70 | 4.20 ± 1.27 |
IC50 values were obtained based on three independent experiments and expressed as mean ± SD.
