Table I.
Incidence of antisynthetase antibodies in individual disease entities in analyzed group of 110 patients
| Disease | Antibody | ||||
|---|---|---|---|---|---|
| Jo-1 | PL-7 | PL-12 | OJ | EJ | |
| Idiopathic inflammatory myopathies | |||||
| Dermatomyositis | 7 | 1 | 1 | 3 | – |
| Polymyositis (PM) | 1 | – | – | – | – |
| Antisynthetase syndrome | 4 | – | 1 | 1 | – |
| Overlap syndrome | |||||
| PM/SLE | – | + | + | + | – |
| PM/RA | – | – | + | – | – |
| PM/scleroderma | – | – | – | – | + |
| Other clinical diagnosis | |||||
| Undifferentiated connective tissue disease | – | 2 | 2 | – | 1 |
| Other diseases* | 5 | 2 | 6 | 1 | 2 |
| No final diagnosis | 6 | 2 | 3 | – | – |
Jo-1 – anti-histidyl tRNA synthetase, PL-7 – anti-threonyl tRNA synthetase, PL-12 – anti-alanyl tRNA synthetase, OJ – anti-isoleucyl tRNA synthetase, EJ – anti-glycyl tRNA synthetase, SLE – systemic lupus erythematosus, RA – rheumatoid arthritis
*
scleroderma, vasculitis, lupus, rheumatoid arthritis, psoriatic arthritis, chronic eosinophilic pneumonia, cutaneous mastocytosis, Sjögren’s syndrome, multiple sclerosis, sarcoidosis, idiopathic interstitial lung disease.