Table 1.
TGF-β subtypes | Clinical stages | Cases | OS | P value | Cases | PFS | P value |
---|---|---|---|---|---|---|---|
HR (95% CI) | HR (95% CI) | ||||||
TGF-β1 | I+II | 135 | 2.62 (1.20-5.73) | 0.0012∗ | 163 | 2.40 (1.36-4.23) | 0.0018∗ |
III+IV | 1220 | 1.11 (0.94-1.30) | 0.21 | 1081 | 0.85 (0.74-0.98) | 0.023∗ | |
| |||||||
TGF-β2 | I+II | 135 | 0.40 (0.18-0.98) | 0.021∗ | 163 | 0.72 (0.41-1.28) | 0.26 |
III + IV | 1220 | 1.21 (1.04-1.40) | 0.011∗ | 1081 | 1.29 (1.12-1.48) | 0.0004∗ | |
| |||||||
TGF-β3 | I+II | 135 | 1.83 (0.69-4.88) | 0.22 | 163 | 1.29 (0.69-2.43) | 0.43 |
III+IV | 1220 | 1.14 (0.98-1.33) | 0.095 | 1081 | 1.36 (1.18-1.56) | 0.001∗ | |
| |||||||
TGF-β4 | I+II | 135 | 2.96 (1.28-6.85) | 0.0079∗ | 163 | 2.18 (1.22-3.87) | 0.0068∗ |
III+IV | 1220 | 0.91 (0.78-1.07) | 0.26 | 1081 | 1.17 (1.02-1.35) | 0.029∗ |
∗ P < 0.05.