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. 2020 Apr 12;2020:2170606. doi: 10.1155/2020/2170606

Table 1.

Correlation of TGF-β subtypes with OS and PFS in ovarian cancer patients with different clinical stages of disease.

TGF-β subtypes Clinical stages Cases OS P value Cases PFS P value
HR (95% CI) HR (95% CI)
TGF-β1 I+II 135 2.62 (1.20-5.73) 0.0012 163 2.40 (1.36-4.23) 0.0018
III+IV 1220 1.11 (0.94-1.30) 0.21 1081 0.85 (0.74-0.98) 0.023

TGF-β2 I+II 135 0.40 (0.18-0.98) 0.021 163 0.72 (0.41-1.28) 0.26
III + IV 1220 1.21 (1.04-1.40) 0.011 1081 1.29 (1.12-1.48) 0.0004

TGF-β3 I+II 135 1.83 (0.69-4.88) 0.22 163 1.29 (0.69-2.43) 0.43
III+IV 1220 1.14 (0.98-1.33) 0.095 1081 1.36 (1.18-1.56) 0.001

TGF-β4 I+II 135 2.96 (1.28-6.85) 0.0079 163 2.18 (1.22-3.87) 0.0068
III+IV 1220 0.91 (0.78-1.07) 0.26 1081 1.17 (1.02-1.35) 0.029

P < 0.05.