Table 2.

Correlation of TGF-β subtypes with OS and PFS in ovarian cancer patients with different pathological grades of disease.

TGF-β subtypes	Pathological grade	Cases	OS	P value	Cases	PFS	P value
			HR (95% CI)			HR (95% CI)
TGF-β1	I	56	0.61 (0.23-1.63)	0.32	37	0.12 (0.02-0.91)	0.0014∗
	II	324	1.41 (0.99-2.01)	0.057	256	0.85 (0.63-1.14)	0.27
	III	1015	1.10 (0.92-1.31)	0.3	837	0.83 (0.69-1.00)	0.056∗
TGF-β2	I	56	0.54 (0.21-1.41)	0.2	37	0.48 (0.12-1.58)	0.22
	II	324	1.40 (1.01-1.95)	0.045∗	256	1.33 (0.98-1.8)	0.069
	III	1015	1.30 (1.1-1.54)	0.0017∗	837	1.42 (1.20-1.68)	0.001∗
TGF-β3	I	56	2.31 (0.89-6.02)	0.076	37	1.90 (0.64-5.66)	0.24
	II	324	1.50 (1.09-2.07)	0.0012∗	256	1.68 (1.25-2.26)	0.0005∗
	III	1015	1.18 (1.00-1.39)	0.053	837	1.32 (1.12-1.57)	0.001∗
TGF-β4	I	56	0.66 (0.24-1.80)	0.42	37	7.86 (1.02-60.55)	0.019∗
	II	324	0.80 (0.59-.08)	0.14	256	0.80 (0.59-1.09)	0.15
	III	1015	1.16 (0.98-1.36)	0.0880	837	1.21 (1.02-1.43)	0.025∗

Notes: pathological grade I (well differentiated), pathological grade II (moderately differentiated), and pathological grade II (poorly differentiated). ^∗P < 0.05.