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. 2020 Apr 22;9(4):480–498. doi: 10.1002/open.202000013

Figure 3.

Figure 3

Sequence‐selective DNA minor‐groove recognition by pyrrole‐imidazole polyamides. a) Schematic representation of the binding of a hairpin polyamide (Py: Pyrrole; Im: Imidazole; Hp: Hydroxypyrrole, adapted from ref. [27]. b) Model of the crystal structure of a polyamide dimer into the DNA minor‐groove (sequence CCAGATCTGG), as extracted from the Protein Data Bank (PDB ID: 1CVY).