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. 2020 Apr 21;323(15):1467–1477. doi: 10.1001/jama.2020.2998

Table 2. Continuous Pulse Oximetry Use in Patients With Bronchiolitis Not Receiving Any Supplemental Oxygen or Nasal Cannula Flow.

Variable No. of patients continuously monitored with pulse oximetry/total No. (%) Unadjusted Adjustedb
OR (95% CI) for use of continuous pulse oximetry P value OR (95% CI) for use of continuous pulse oximetry P value
Category Compositea Category Compositea
Overall (n = 56 hospitals) 1679/3612 (46) NA NA NA NA NA NA
Agec .11 <.001
8 wk-5 mo
Preterm 103/183 (56) 1.78 (1.12-2.83) .02 2.58 (1.65-4.02) <.001
Not preterm 758/1559 (49) 1.31 (1.03-1.66) .03 1.51 (1.12-2.03) .007
6-11 mo
Preterm 47/107 (44) 1.08 (0.74-1.59) .68 1.21 (0.72-2.05) .48
Not preterm 402/894 (45) 1.13 (0.89-1.43) .31 .14
12-17 mo
Preterm 20/48 (42) 0.99 (0.52-1.86) .97 0.77 (0.38-1.58) .48
Not preterm 219/512 (43) 1.03 (0.74-1.45) .85 1.01 (0.72-1.42) .95
18-23 mo
Preterm 10/23 (43) 1.06 (0.46-2.47) .89 0.50 (0.18-1.37) .18
Not preterm 120/286 (42) 1 [Reference] 1 [Reference]
Sex .52 Not includedb
Male 977/2125 (46) 1 [Reference]
Female 702/1485 (47) 1.05 (0.90-1.23) .52
Raced .61 Not includedb
White 938/2034 (46) 1 [Reference]
Other 502/1025 (49) 1.12 (0.82-1.53) .47
Black or African American 239/553 (43) 0.90 (0.62-1.28) .53
Ethnicityd .11 Not includedb
Not Hispanic or Latino 1088/2454 (44) 1 [Reference]
Hispanic or Latino 410/766 (54) 1.45 (1.05-1.98) .02
Unknown 123/259 (48) 1.14 (0.77-1.68) .53
Other 58/133 (44) 0.97 (0.62-1.51) .90
Time since weaning from supplemental oxygen or flow, he <.001 <.001
Never received 442/1190 (37) 1 [Reference] 1 [Reference]
<1 59/80 (74) 4.75 (1.90-11.93) .001 5.01 (2.76-9.07) <.001
1-<2 108/148 (73) 4.57 (2.50-8.35) <.001 5.97 (3.84-9.30) <.001
2-<4 166/244 (68) 3.60 (2.31-5.61) <.001 5.55 (3.91-7.89) <.001
4-<6 135/234 (58) 2.31 (1.49-3.58) <.001 2.96 (2.13-4.13) <.001
6-<12 276/505 (55) 2.04 (1.42-2.93) <.001 2.12 (1.65-2.72) <.001
12-<24 302/687 (44) 1.33 (0.98-1.80) .07 1.16 (0.93-1.45) .20
≥24 179/499 (36) 0.95 (0.68-1-31) .74 0.75 (0.58-0.97) .03
Intensive care unit stay during present hospitalization .54 Not includedb
Yes 424/884 (48) 1.08 (0.84-1.39) .54
No 1255/2728 (46) 1 [Reference]
Apnea or cyanosisf .02 .04
Yes 128/235 (54) 1.41 (1.07-1.86) .02 1.40 (1.01-1.93) .04
No 1551/3377 (46) 1 [Reference] 1 [Reference]
Comorbid condition associated with neurologic impairmentg .08 .10
Yes 51/93 (55) 1.41 (0.96-2.06) .08 1.50 (0.93-2.43) .10
No 1628/3519 (46) 1 [Reference] 1 [Reference]
Enteral feeding tube in placeh <.001 <.001
Yes 176/305 (58) 1.64 (1.23-2.17) <.001 1.98 (1.46-2.67) <.001
No 1503/3307 (45) 1 [Reference] 1 [Reference]
Hospital type .58 Not includedb
Freestanding children’s hospital (n = 33) 1198/2667 (45) 1 [Reference]
Children's hospital within hospital (n = 14) 317/591 (54) 1.42 (0.74-2.73) .29
Community hospital (n = 9) 164/354 (46) 1.06 (0.55-2.02) .86
Time of day observation performed <.001 <.001
Day (10 am to 5 pm) 870/2073 (42) 1 [Reference] 1 [Reference]
Night (11 pm to 7 am) 809/1539 (53) 1.53 (1.27-1.85) <.001 2.07 (1.76-2.43) <.001

Abbreviation: OR, odds ratio.

a

In variables with multiple categories, composite P value was obtained using the Wald test.

b

The following variables met the prespecified criteria to be included in the multivariable model: age and gestational age category, time since weaning from supplemental oxygen or flow, apnea or cyanosis, comorbid condition associated with neurologic impairment, enteral feeding tube, and time of day observation was performed. Ethnicity met initial criteria to enter the model based on having a bivariable association composite P value less than .20 but was eliminated from the multivariable model for a composite P value of .34.

c

Not preterm included the following: documented gestational age 34 0/7 weeks and above, absence of gestational age but documented as full term, or absence of gestational age but not labeled in chart as preterm or premature.

d

Patient family-reported race and ethnicity were abstracted from charts in categories defined by the Standards for the Classification of Federal Data on Race and Ethnicity, in compliance with National Institutes of Health inclusion reporting policies. In this Table, “other” race includes all of the following categories: American Indian or Alaska Native, Asian, Native Hawaiian or Pacific Islander, specified as more than one race, specified as other, and specified as unknown.

e

Individuals with unknown time since weaning (n = 25) are not included.

f

Includes documentation of apnea or cyanosis occurring at home or in the hospital during the present illness.

g

Static encephalopathy, cerebral palsy, hydrocephalus, spina bifida, epilepsy/seizure disorder, or hypotonia.

h

Nasogastric or gastrostomy.