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. 2020 Mar 13;10(3):0. doi: 10.3390/biom10030450

Figure 1.

Figure 1

Isolation and characterization of fibroblasts from mitochondrial disease patients. (A) Overview of cell lines used in this study. (B) Heteroplasmy rate measured by restriction fragment length polymorphism (RFLP). The 3243A>G mutation was digested by Apa1, while the 10158T>C mutation was not digested by Taq1. MELAS: Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.