Figure 2.

An overview of the different AAA⁺ protein clades. All AAA⁺ proteins form higher order homo- or hetero-oligomers that form asymmetric ring structures with heterogeneous nucleotide occupancies (28–33). All monomers contain a nucleotide binding site for ATP, and additional insertions (highlighted in orange on the monomer structures) that aid their unique functions. For monomeric structures: α-helices are coloured in blue; β-sheets, pink; insertions, orange and nucleotide and nucleotide analogues coloured by heteroatom.