Table 2.
Agreements of level 1, 2, and 3 readings for referable (>R2) diabetic retinopathy and diabetic macular edema (>M1) and referral to ophthalmology for all eyes versus the consensus gold standard (level 1 reading [n=266] and level 2 reading [n=1118]).
| Reader | Consensus gold standard referable diabetic retinopathy, κa (95% CI) | Consensus gold standard referable diabetic macular edema grading, κ (95% CI) | Consensus gold standard referral to ophthalmology, κ (95% CI) | |
| Level 1 reading (n=266) | ||||
|
|
Reader A (n=114) | N/Ab | N/A | 0.859 (0.764-0.953) |
|
|
Level 3 reader for reader A | N/A | N/A | 1.00 (1.000-1.000) |
|
|
Reader B (n=152) | N/A | N/A | 0.803 (0.709-0.896) |
|
|
Level 3 reader for reader B | N/A | N/A | 1.00 (1.000-1.000) |
| Level 2 reading (n=1118) | ||||
|
|
Reader A (n=646) | 0.803 (0.757-0.850) | 0.788 (0.733-0.842) | 0.757 (0.677-0.838) |
|
|
Level 3 reader for reader A | 0.940 (0.912-0.968) | 0.961 (0.935-0.986) | 0.967 (0.935-0.999) |
|
|
Reader B (n=472) | 0.826 (0.777-0.874) | 0.877 (0.830-0.925) | 0.887 (0.822-0.952) |
|
|
Level 3 reader for reader B | 0.957 (0.930-0.983) | 0.946 (0.914-0.979) | 0.936 (0.886-0.987) |
aκ: kappa coefficient. All kappas have P values <.001.
bNot applicable.