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. 2020 Mar 18;10(3):467. doi: 10.3390/biom10030467

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Immunohistochemical (IHC) assessment of HO-1 and ANXA2 in a human tissue micro arrays (TMA). Prostate disease spectrum tissue microarray was used for the IHC analyses, containing 32 cases of adenocarcinoma, two metastasis, 26 hyperplasia, six chronic inflammation, six cancer adjacent prostate tissue, and eight normal tissue. (A) Pie chart shows the distribution of the disease stages analyzed in the TMA. (B) Representative images for adenocarcinoma, BPH, chronic inflammation, and normal gland stained with H&E or immunoassayed for Annexin 2 or HO-1. (C) Graph represents the percentage of positive samples for ANXA2 or HO-1 immunostaining across the different prostate tissue samples.