Figure 2.
NAD+ biology-targeting treatment strategies for obesity- and aging-related metabolic and circadian disorders. CD38: cyclic ADP-ribose cyclase/cluster of differentiation 38, CD73: ecto-5′-nucleotidase/cluster of differentiation 73, NAD+: nicotinamide adenine dinucleotide, NAMPT, nicotinamide phosphoribosyltransferase, NMN, nicotinamide mononucleotide, NMNAT: nicotinamide mononucleotide adenylyltransferase, NR: nicotinamide riboside, NRK: nicotinamide riboside kinase, and PARP: poly(ADP-ribose) polymerases.