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. 2020 Feb 27;8(3):45. doi: 10.3390/biomedicines8030045

Figure 1.

Figure 1

Effect of nanoparticles on NFκB luciferase reporter activation. Human SH-SY5Y cells (2 × 104/well) expressing a NFκB reporter gene (transfected plasmid—pNFκB-Lu-neo) were exposed to concentrations of nanoparticles (NPs) of CuO, Fe2O3, and ZnO at a range of 0 to 100 μM/mL for 6 h. Luciferase reagent was added and luciferase activation signals were measured using a Veritas™ microplate luminometer. Results are expressed as fold induction. * p < 0.01, ** p < 0.001, *** p < 0.0001, for CuONPs (10 μM, 100 μM) compared to control, untreated, # p < 0.01 for Fe2O3NPs compared to control, ^ p < 0.01 for ZnONPs compared to control.