Figure 6.

MetaCore protein network of murine NAGLU^−/− brain proteome. The protein–protein interactions characterizing the murine NAGLU^−/− brain proteome, were explored by MetaCore tools. The experimental proteins (blue circles) were processed according to known protein–protein interactions and other features established in the literature. The relationships existing between individual proteins and their directions were represented by arrows and lines. The following line colors designate the nature of the interaction: red = negative effect, green = positive effect, gray = unspecified effect.