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. 2020 Feb 25;8(3):43. doi: 10.3390/biomedicines8030043

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The expression of TGF-β by immunostaining in different groups. (A) Graphs of ROI of the expression of TGF-β in different groups. Heart specimens showing (B) negative TGF-β expression (control group), (C) marked membranous expression of TGF-β within the interstitial tissue between fibers (arrows) (DM group), (D) moderate membranous expression of TGF-β (arrows) (DM + GLP1 group), and (E) minimal membranous expression of TGF-β (arrows) (DM + SGLT2i group). * Significant vs. control group, ^# significant vs. DM group and ^$ significant vs. GLP1 group.