Figure 2.

Ablation of Arf-expressing cells ameliorated CS-induced lung pathologies. (a) Representative images of ARF-DTR lung sections stained with hematoxylin and eosin. Bar; 50 μm. (b) Alveolar mean linear intercepts were measured. (c) The number of macrophages per field (×40) was counted. At least 8 fields were analyzed in each mouse. (d) The expression of Mmp-12 was analyzed by real-time PCR. Data were normalized to Gapdh in each group. Bars represent means ± SEM. Data were analyzed by a one-way ANOVA and Tukey post-hoc analysis. ** p < 0.01 and ns; not significant.