Table 1. Number of activated and dormant follicles on day 5 after the transplantation of biodegradable gels.
No. of mouse - L/R | Number of primordial follicles | R/L (ratio of activated primordial follicles) | ||
---|---|---|---|---|
active (/total) | dormant | |||
Control | ||||
1-L | 81 (0.27) | 223 | 0.62 | |
1-R | 50 (0.17) | 251 | ||
2-L | 116 (0.20) | 471 | 0.97 | |
2-R | 112 (0.19) | 474 | ||
3-L | 63 (0.24) | 200 | 0.76 | |
3-R | 49 (0.18) | 219 | ||
4-L | 75 (0.17) | 372 | 0.83 | |
4-R | 45 (0.14) | 278 | ||
5-L | 59 (0.18) | 265 | 0.98 | |
5-R | 56 (0.18) | 259 | ||
VEGF 100 ng/ml | ||||
1-L | 122 (0.25) | 359 | 0.82 | |
1-R | 112 (0.21) | 428 | ||
2-L | 86 (0.17) | 359 | 0.95 | |
2-R | 81 (0.16) | 434 | ||
3-L | 46 (0.20) | 187 | 0.97 | |
3-R | 57 (0.19) | 242 | ||
4-L | 73 (0.31) | 166 | 0.76 | |
4-R | 57 (0.23) | 188 | ||
VEGF 1 μg/ml | ||||
1-L | 38 (0.18) | 172 | 1.00 | |
1-R | 37 (0.18) | 167 | ||
2-L | 37 (0.17) | 178 | 1.14 | |
2-R | 49 (0.20) | 200 | ||
3-L | 79 (0.27) | 214 | 1.08 | |
3-R | 77 (0.29) | 187 | ||
4-L | 54 (0.29) | 133 | 0.92 | |
4-R | 68 (0.26) | 189 | ||
VEGF 10 μg/ml | ||||
1-L | 49 (0.16) | 252 | 1.22 | |
1-R | 65 (0.20) | 262 | ||
2-L | 47 (0.16) | 253 | 1.07 | |
2-R | 42 (0.17) | 208 | ||
3-L | 11 (0.20) | 45 | 1.40 | |
3-R | 19 (0.28) | 50 |
The averages of R/L for each group are shown in Fig. 2B. L, left ovary; R, right ovary. VEGF, vascular endothelial growth factor.