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SFN treatment downregulated expression of glycolysis-related proteins in PIN lesions of Hi-Myc mice. Immunohistochemical images for HKII, PKM2 and LDHA protein expression in representative prostate sections of control and SFN-treated Hi-Myc mice (×40 objective magnification, scale bar = 50 µm) are shown in the left panel. Quantitative data for H-score are shown are mean ± SD (n = 5) in the right panel. Statistical analysis was performed by Student’s t-test (*P < 0.05).
