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. 2020 Apr 21;12:57. doi: 10.1186/s13148-020-00849-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — S5 score distributions by histological diagnosis: no lesion, LSIL, HSIL, and cervical cancer (CC). No lesion vs HSIL (p < 0.001), no lesion vs CC (p < 0.001), LSIL vs HSIL (p < 0.001), LSIL vs CC (p < 0.001), and HSIL vs CC (p < 0.001). The middle line is the median; the Cuzick test for trend was significant (p < 0.001). The upper whisker extends to the largest point of the inter-quartile range from the upper quartile. The lower whisker extends to the smallest point of the inter-quartile range from the lower quartile. No lesion, histologically negative without squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; CC, cervical cancer