Table 1.

Prediction performance based on hyper-DMS and hypo-DMS to distinguish between disease and normal colorectal tissues

Model	Methylation	Observation	Prediction		Sensitivity	Specificity
			Disease	Normal
Random forest	Hyper	Disease	532	23	0.959	0.860
		Normal	39	239
	Hypo	Disease	507	48	0.914	0.601
		Normal	111	167
Neural network	Hyper	Disease	537	18	0.968	0.727
		Normal	76	202
	Hypo	Disease	406	149	0.732	0.701
		Normal	83	195