Table 2.

Statistics of the mutations found in e8 mutant strain

Total SNPs	Predicted effect
	Low	Moderate	High	Other
240	36	80	1	123SNPs

Total number of SNPs found is reported in the first column. The predicted effect of mutations are reported according to SNPeff software: HIGH is for mutation probably causing protein truncation, loss of function or triggering nonsense-mediated decay, Moderate are non-disruptive variants that might change protein effectiveness and LOW are mutations harmless or unlikely to change protein behavior. SNPs with predicted non-coding variants or variants affecting non-coding genes, where predictions are difficult or there is no evidence of impact were not considered: the number of remaining SNPs is reported in the last column (Other)