Table 6.
Outcome | Lovastatin+PILI | Placebo+PILI | ||
---|---|---|---|---|
Baseline | Post | Baseline | Post | |
Receptive vocab growth score | 134.75 ± 31.76 | 136.92 ± 33.87 | 137.44 ± 22.71 | 136.44 ± 19.79 |
Expressive vocab growth score | 143.5 ± 22.12 | 142.67 ± 24.53 | 141.44 ± 14.45 | 142.75 ± 12.91 |
Expressive grammar raw score | 10.18 ± 11.36 | 11 ± 12.66 | 8.33 ± 6.41 | 9.93 ± 7.59 |
Receptive grammar raw score | 22.18 ± 18.91 | 22.17 ± 20.23 | 21.4 ± 9.26 | 20.2 ± 11.98 |
Parent strategy: recasts | 3.28 ± 2.67 | 29.67 ± 13.34 | 5.48 ± 5.07 | 24.79 ± 12.57 |
Parent strategy: WH-questions | 9.56 ± 9.06 | 40.36 ± 20.69 | 13.19 ± 8.57 | 33.25 ± 17.73 |
Parent strategy: fill-in-the-blank prompts | 2.06 ± 2.74 | 19.56 ± 11.96 | 3.21 ± 6.96 | 16.5 ± 14.24 |
ABC-C – total score | 44.5 ± 28.43 | 40.5 ± 31.83 | 55.5 ± 30.18 | 44.06 ± 25.36 |
RBS-R – total score | 27.75 ± 17.43 | 28.67 ± 23.9 | 32.19 ± 18.84 | 26.19 ± 20.14 |
Clinical Global Impression (CGI) | 4.581 ± 0.67 | 2.422 ± 0.67 | 4.501 ± 0.63 | 2.382 ± 0.72 |
VAS: spoken language impairment | 4.06 ± 2.43 | 5.66 ± 1.99 | 1.94 ± 1.41 | 4.18 ± 1.53 |
VAS: social impairment | 3.73 ± 1.74 | 5.18 ± 1.70 | 2.55 ± 1.36 | 3.99 ± 2.06 |
1CGI-severity ratings collected at baseline visit
2CGI-improvement ratings collected at post-treatment visit