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. 2020 Apr 22;12:12. doi: 10.1186/s11689-020-09315-4

Table 6.

Group comparison (mean ± SD) in secondary outcome measures between patients on lovastatin vs. placebo

Outcome Lovastatin+PILI Placebo+PILI
Baseline Post Baseline Post
Receptive vocab growth score 134.75 ± 31.76 136.92 ± 33.87 137.44 ± 22.71 136.44 ± 19.79
Expressive vocab growth score 143.5 ± 22.12 142.67 ± 24.53 141.44 ± 14.45 142.75 ± 12.91
Expressive grammar raw score 10.18 ± 11.36 11 ± 12.66 8.33 ± 6.41 9.93 ± 7.59
Receptive grammar raw score 22.18 ± 18.91 22.17 ± 20.23 21.4 ± 9.26 20.2 ± 11.98
Parent strategy: recasts 3.28 ± 2.67 29.67 ± 13.34 5.48 ± 5.07 24.79 ± 12.57
Parent strategy: WH-questions 9.56 ± 9.06 40.36 ± 20.69 13.19 ± 8.57 33.25 ± 17.73
Parent strategy: fill-in-the-blank prompts 2.06 ± 2.74 19.56 ± 11.96 3.21 ± 6.96 16.5 ± 14.24
ABC-C – total score 44.5 ± 28.43 40.5 ± 31.83 55.5 ± 30.18 44.06 ± 25.36
RBS-R – total score 27.75 ± 17.43 28.67 ± 23.9 32.19 ± 18.84 26.19 ± 20.14
Clinical Global Impression (CGI) 4.581 ± 0.67 2.422 ± 0.67 4.501 ± 0.63 2.382 ± 0.72
VAS: spoken language impairment 4.06 ± 2.43 5.66 ± 1.99 1.94 ± 1.41 4.18 ± 1.53
VAS: social impairment 3.73 ± 1.74 5.18 ± 1.70 2.55 ± 1.36 3.99 ± 2.06

1CGI-severity ratings collected at baseline visit

2CGI-improvement ratings collected at post-treatment visit