. 2020 Apr 22;12:12. doi: 10.1186/s11689-020-09315-4

Table 9.

Group comparison (mean ± SD) in molecular biomarkers between patients on lovastatin vs. placebo

Biomarker	Lovastatin+PILI			Placebo+PILI			Between-group comparison
Biomarker	Baseline	Post	Within-group: baseline vs. post	Baseline	Post	Within-group: baseline vs. post	Baseline	Post	Post, adjusted for baseline
MMP	6.36 ± 2.84	6.25 ± 2.48	t₍₁₁₎ = − 0.09 (0.9313)	6.69 ± 3.65	7.20 ± 4.10	t₍₁₂₎ = − 0.99 (0.3407)	F_{(1, 24)} = 0.01 (0.9383)	F_{(1, 23)} = 0.18 (0.675)	F_{(1, 22)} = 0.48 (0.4935)
ERK	0.48 ± 0.26	0.58 ± 0.32	t₍₁₁₎ = − 0.62 (0.5502)	0.50 ± 0.22	0.84 ± 0.98	t₍₁₂₎ = − 1.16 (0.2676)	F_{(1, 23)} = 0.16 (0.6911)	F_{(1, 23)} = 0.57 (0.4599)	F_{(1, 22)} = 0.64 (0.4332)
S6K	0.11 ± 0.10	0.11 ± 0.11	t (11) = 1.11 (0.2891)	0.14 ± 0.26	0.08 ± 0.04	t₍₁₁₎ = 0.66 (0.5203)	F_{(1, 23)} = 0.08 (0.7772)	F_{(1, 22)} = 0.07 (0.7878)	F_{(1, 21)} = 0.09 (0.772)