Table 5.
Total timea required for contact management and LTBI care for all steps along the LTBI Cascade of Care
| Identify contacts | Place TSTb | Read TSTb | Conduct Medical Evaluationb,c | Recommend and Discuss LTBI Treatmentb,c | LTBI Follow-up Visitb,c,d | Total Time Per Index Case (hours) | |
|---|---|---|---|---|---|---|---|
| Country | (A) | (B) | (C) | (D) | (E) | (F) | Σ (A-F) |
| LMIC | |||||||
| Benin | |||||||
| Doctors | - | - | - | 18.9 | 10.7 | - | 0.50 |
| Nurses | 7.5 | 17.6 | 11.3 | - | 14.0 | 63.4 | 1.90 |
| Ghana | |||||||
| Doctors | - | - | - | 42.7 | 24.2 | - | 1.12 |
| Nurses | 7.5 | 39.6 | 25.5 | - | 31.7 | 143.0 | 4.12 |
| Indonesia | |||||||
| Doctors | - | - | - | 16.0 | 9.1 | - | 0.42 |
| Nurses | 7.5 | 14.9 | 9.6 | - | 11.9 | 53.6 | 1.63 |
| Vietnam | |||||||
| Doctors | - | - | - | 13.6 | 7.7 | - | 0.36 |
| Nurses | 7.5 | 12.6 | 8.1 | - | 10.1 | 45.5 | 1.40 |
| High-Income | |||||||
| Canada | |||||||
| Doctors | - | - | - | 13.1 | 14.3 | - | 0.46 |
| Nurses | 12.8 | 56.9 | 43.2 | - | 16.0 | 44.4 | 2.89 |
aPredicted time (min) for each step from linear mixed models (LMM) shown in Supplementary Tables S1–5
bAssumes step accounts for all household contacts (HHC) for one index case; based on average number of HHC per index patient in each country observed in the main study: Benin = 3.9; Ghana = 8.8; Indonesia = 3.3; Vietnam = 2.8; Canada = 3.6
cAssumes a prevalence of TST positive for HHC of index patient is 50% in LMIC and 28% in Canada (Fox 2013)
dAssumes 5 follow-up visits for 6 months of INH treatment of LTBI in LMIC and 3 follow-up visits for 4 months of RIF treatment of LTBI in Canada