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. 2020 Apr 22;17:125. doi: 10.1186/s12974-020-01740-5

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — The effect of SAHA administration on bone destruction following TCI. a 2D representative MicroCT images of trabecular bone microarchitecture. b Quantitative analysis of the BMD in tibia of the TCI + vehicle and the TCI + SAHA group (n = 4). Data are expressed as the mean ± SEM. Representative images of HE staining showing cancer cell infiltration (cells within the dotted lines) and bone resorption pits (arrows) on trabecular surface in tibial marrow cavity of the TCI + vehicle (b (i, ii)) and TCI + SAHA (b (ii, iii)) group. Original magnification: 100 (upper row), 200 (bottom row)