Table 1.
The comparison of demographic and clinical characteristics between patients hospitalized with FluA-p and FluB-p in China, 2013–2019
| Variable | Total (n = 1079) | FluA-p (n = 693) | FluB-p (n = 386) | P-value |
|---|---|---|---|---|
| Age (years, median, IQR) | 61.0 (49.0–78.0) | 61.0 (36.0–73.0) | 67.0 (55.0–80.0) | <0.001 |
| Male (n, %) | 584 (54.1) | 461 (66.5) | 123 (31.9) | <0.001 |
| Days from disease onset to admission (median, IQR) | 3.0 (2.0–4.0) | 3.0 (2.0–4.0) | 3.0 (2.0–4.3) | 0.082 |
| Comorbidities (n, %) | ||||
| Cardiovascular disease | 259 (24.0) | 136 (19.6) | 123 (31.9) | <0.001 |
| Cerebrovascular disease | 97 (9.0) | 72 (10.4) | 25 (6.5) | 0.031 |
| Diabetes Mellitus | 127 (11.8) | 92 (13.3) | 35 (9.1) | 0.040 |
| COPD | 91 (8.4) | 40 (5.8) | 51 (13.2) | <0.001 |
| Asthma | 33 (3.0) | 19 (2.7) | 14 (3.6) | 0.418 |
| Chronic kidney disease | 30 (2.8) | 16 (2.3) | 14 (3.6) | 0.207 |
| Solid Malignant tumor | 24 (2.2) | 16 (2.3) | 8 (2.1) | 0.801 |
| Obesity | 76 (7.0) | 48 (6.9) | 28 (7.3) | 0.840 |
| Pregnancy | 8 (0.7) | 8 (1.2) | 0 (0.0) | 0.080 |
| Smoking history | 313 (29.0) | 243 (35.1) | 70 (18.1) | <0.001 |
| Baseline clinical and radiologic features (n, %) | ||||
| Axillary temperature ≥ 38 °C | 814 (75.4) | 661 (95.4) | 153 (39.6) | <0.001 |
| Cough/sputum | 1060 (98.2) | 679 (98.0) | 381 (98.7) | 0.386 |
| Confusion | 150 (13.9) | 32 (4.6) | 118 (30.6) | <0.001 |
| Respiratory rates ≥ 30 beats/min | 146 (13.5) | 121 (17.5) | 25 (6.5) | <0.001 |
| SBP < 90 mmHg | 15 (1.4) | 8 (1.2) | 7 (1.8) | 0.375 |
| Leukocytes > 10 × 109/L | 283 (26.2) | 118 (17.0) | 165 (42.7) | <0.001 |
| Lymphocytes < 0.8 × 109/L | 480/1063 (45.2) | 299/677 (44.2) | 181 (46.9) | 0.390 |
| HB < 100 g/L | 240 (22.2) | 69 (10.0) | 171 (44.3) | <0.001 |
| ALB < 35 g/L | 187/1025 (18.2) | 58/639 (9.1) | 129 (33.4) | <0.001 |
| BUN > 7 mmol/L | 446/1071 (41.6) | 183/685 (26.7) | 263 (68.1) | <0.001 |
| Arterial pH < 7.35 | 171/1025 (16.7) | 120/639 (18.8) | 51 (12.7) | 0.021 |
| PO2/FiO2 < 300 mmHg | 480/1025 (46.8) | 340/639 (53.2) | 140 (36.3) | <0.001 |
| Multilobar infiltrates | 794 (73.6) | 546 (78.8) | 248 (64.2) | <0.001 |
| Coinfections (n, %) | 367 (34.0) | 265 (38.2) | 102 (26.4) | <0.001 |
IQR Interquartile range, COPD Chronic obstructive pulmonary disease; SBP Systolic blood pressure, HB Haemoglobin, ALB Albumin, BUN Blood urea nitrogen, pH Hydrogen ion index, PO2/FiO2 Arterial pressure of oxygen/fraction of inspiration oxygen