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. 2020 Apr 22;13:63. doi: 10.1186/s13041-020-00601-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Arginine inhibits MCAO-induced inflammatory response by the suppression of LDHA. a RT-PCR shows that the increased pro-inflammatory response in MCAO rats is inhibited by FX11. FX11 occludes the pro-inflammation inhibition of arginine (n = 6 in each group, *p < 0.05 versus I/R, one-way ANOVA test). b RT-PCR shows that anti-inflammation is enhanced by FX11 in MCAO rats. FX11 occludes anti-inflammation upregulation by arginine (n = 6 in each group, *p < 0.05 versus I/R, one-way ANOVA test)