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Schematic representation of the repair of peripheral nerve damage with a stem cell-based tissue-engineered nerve graft. Stem cells are isolated, cultured, expanded and incorporated into a neural scaffold containing an outer porous nerve conduit and numerous inner luminal fillers to construct a stem cell-based tissue-engineered nerve graft. Implanted stem cells differentiate into Schwann cells, secrete neurotrophic factors and promote peripheral nerve regeneration
