Table 1.
Baseline demographics and clinical characteristics in survivors and nonsurvivors at ICU discharge of two groups
| Variables | Experimental group | Validation group | ||||||
|---|---|---|---|---|---|---|---|---|
| All | Survivors | Nonsurvivors | P | All | Survivors | Nonsurvivors | P | |
| n = 626 | n = 378 | n = 248 | n = 268 | n = 190 | n = 78 | |||
| Demographic | ||||||||
| Age (years) | 68.0 (55.0, 80.0) | 68.5 (55.0, 80.0) | 68.0 (55.0, 79.5) | 0.728 | 68.0 (58.0, 80.0) | 64.0 (54.0, 77.0) | 75.0 (65.0, 82.0) | 0.000 |
| Sex (male), n (%) | 394 (62.9) | 229 (60.6) | 163 (65.7) | 0.193 | 169 (63.1) | 125 (65.8) | 44 (56.4) | 0.148 |
| BMI | 22.9 (21.0, 24.9) | 23.0 (21.1, 24.7) | 22.9 (20.8, 25.0) | 0.354 | 22.7 (20.5, 24.5) | 22.8 (20.8, 24.5) | 22.3 (19.6, 24.2) | 0.134 |
| Clinical | ||||||||
| Admission Category, n (%) | ||||||||
| Medical | 412 (65.8) | 237 (62.7) | 175 (70.6) | 0.011 | 225 (84.0) | 152 (80.0) | 73 (93.6) | 0.010 |
| Surgical | 214 (34.2) | 141 (37.3) | 73 (29.4) | 0.011 | 43 (16.0) | 38 (20.0) | 5 (6.4) | 0.010 |
| Severity of illness, n (%) | ||||||||
| MV | 469 (74.9) | 246 (65.1) | 223 (89.9) | 0.000 | 185 (69.0) | 116 (61.1) | 69 (88.5) | 0.000 |
| CRRT | 111 17.7) | 36 (9.5) | 75 (30.2) | 0.000 | 38 (14.2) | 13 (6.8) | 25 (32.1) | 0.000 |
| Sepsis | 325 (51.9) | 227 (60.0) | 98 (39.5) | 0.000 | 128 (47.8) | 105 (55.3) | 23 (29.5) | 0.000 |
| Septic shock | 301 (48.1) | 151 (39.9) | 150 (60.4) | 0.000 | 140 (52.2) | 85 (44.7) | 55 (70.5) | 0.000 |
| CCI | 1 (0, 2) | 1 (0, 2) | 2 (1, 2) | 0.001 | 1 (0, 2) | 1 (0, 2) | 2 (1, 3) | 0.000 |
| Primary sites of infection, n (%) | ||||||||
| Lungs | 333 (53.2) | 180 (47.6) | 153 (61.7) | 0.001 | 144 (53.7) | 94 (49.5) | 50 (64.1) | 0.029 |
| Thoracic cavity | 11 (1.8) | 7 (1.9) | 4 (1.6) | 1.000 | 8 (3.0) | 7 (3.7) | 1 (1.3) | 0.513 |
| Abdomen | 162 (25.9) | 110 (29.1) | 52 (21.0) | 0.023 | 65 (24.3) | 52 (27.4) | 13 (16.7) | 0.063 |
| Urinary tract | 30 (4.8) | 19 (5.0) | 11 (4.4) | 0.157 | 7 (2.6) | 7 (3.7) | 0 (0.0) | 0.195 |
| Bacteremia | 38 (6.1) | 15 (4.0) | 23 (9.3) | 0.007 | 17 (6.3) | 11 (5.8) | 6 (7.7) | 0.562 |
| Catheter | 3 (0.5) | 1 (0.3) | 2 (0.8) | 0.712 | 2 (0.7) | 1 (0.5) | 1 (1.3) | 1.000 |
| Soft tissue | 15 (2.4) | 9 (2.4) | 6 (2.4) | 0.975 | 10 (3.7) | 9 (4.7) | 1 (1.3) | 0.317 |
| Nervous system | 6 (1.0) | 4 (1.1) | 2 (0.8) | 1.000 | 2 (0.7) | 0 (0.0) | 2 (2.6) | 0.152 |
| Hospital days | 16 (9, 27) | 17 (10, 28) | 15 (6, 24) | 0.003 | 19 (11, 30) | 20 (11, 31) | 15 (9, 25) | 0.007 |
BMI body mass index, CCI Charlson Comorbidity Index, CRRT continuous renal replacement therapy, ICU intensive care unit, MV mechanical ventilation. Continuous variables are presented as mean ± standard deviation or median and interquartile range when not normally distributed. Categorical variables are presented as number (%)