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. Author manuscript; available in PMC: 2020 Apr 22.
Published in final edited form as: Bioconjug Chem. 2018 Jun 12;29(7):2195–2207. doi: 10.1021/acs.bioconjchem.8b00104

Scheme 1.

Scheme 1.

General Synthetic Pathway for the Preparation of the Anthraquinone Derivatives Included in the Studya

aReagents and conditions: (i) Pyridine, DMF; (ii) 33% Diethylamine, THF; (iii) TFA/H2O; (iv) HBTU, DMAP, DMF; (v) 33% Diethylamine, THF; (vi) TFA/H2O.