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. Author manuscript; available in PMC: 2020 Apr 22.
Published in final edited form as: Bioconjug Chem. 2018 Jun 12;29(7):2195–2207. doi: 10.1021/acs.bioconjchem.8b00104

Table 2.

Inhibition of NC-Mediated Annealing of TAR/cTAR Assessed by NAME Assay

compound IC50 NAMEa (μM)
D-4a >100
D-4b >100
D-4c >100
D-4d >100
D-4e 76.7 ± 8.61
D-4f 78.8 ± 10.8
D-4g 37.5 ± 13.6
D-4h 28.9 ± 4.59
D-4i >100
a

Values represent the mean and standard error of the mean (SEM) obtained from experiments performed in triplicate