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. 2020 Apr 15;11:619. doi: 10.3389/fmicb.2020.00619

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Copyright © 2020 Nyong, Zaia, Allué-Guardia, Rodriguez, Irion-Byrd, Koenig, Feng, Bono and Eppinger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chromosomal virulence gene inventory of Stx (±) NSF O157:H7 and SF O157:NM. Predicted virulence genes in each sampled genome were identified with VirulenceFinder (Joensen et al., 2014; Kleinheinz et al., 2014). Identities for each gene are visualized in a heatmap using MeV (Saeed et al., 2003). The order of query chromosomes reflects the phylogenomic position in the stepwise model of O157:H7 evolution. Besides the absence of Stx-phages or disruption of stx genes, the sampled stx (–) strains resemble the virulence profile of Stx (+) O157:H7/NM. Stars indicate the fragmentary status of the tccP and espF loci in the respective draft genomes.