NCT00429442.

Trial name or title	Simvastatin as an Add‐on Treatment to Copaxone for the Treatment of Relapsing Multiple Sclerosis
Methods	A Double Blind, Randomised, Placebo Controlled Study
Participants	20 patients with Relapsing‐remitting MS Between the age of 18 and 60 years (both included) EDSS of 6.5 or less 20 Written informed consent
Interventions	Intervention group: copaxone and simvastatin 80 mg Control group: copaxone and calcium tablets
Outcomes	Primary outcomes: number of new and/or enlarging lesions on T2‐ weighted MRI. Secondary Outcomes: changes in the EDSS and MFSC score, number of documented relapses.
Starting date	March 2008
Contact information	Jette L Frederiksen, DMSC, Department of Neurology, Glostrup Hospital, Denmark Tel: +45 43233041; Email: jefr@glo.regionh.dk Anna Tsakiri, MD; Tel: +45 43233524; Email: ants@dadlnet.dk
Notes	Sponsored by Sanofi‐Aventis http://clinicaltrials.gov/ct2/show/NCT00429442