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. 2020 Apr 15;10:438. doi: 10.3389/fonc.2020.00438

Figure 1.

Figure 1

piR-004800 was highly expressed in MM patients and MM cell lines. (A) The heatmap for the differentially expressed piRNAs between the exosomes from normal and MM bone marrow supernatant. (B) Expression levels of piR-004800 in exosomes from bone marrow supernatant in MM patients (n = 56) and healthy donors (n = 17) were tested by qRT-PCR. (C) piR-004800 expression levels in CD138+ cells from MM patients (n = 29) and in bone marrow mononuclear cells from healthy donors (n = 18) were tested by qRT-PCR. (D) The expression of piR-004800 in MM patients with different ISS stages. ISS I (n = 11); ISS II (n = 15); ISS III (n = 30). (E) piR-004800 expression levels in MM cell lines and normal bone marrow mononuclear cells were tested by qRT-PCR. (F) piR-004800 expression levels in MM cell lines' exosomes and exosomes from bone marrow supernatant in healthy donors were tested by qRT-PCR. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.