Table 4.

ROC and AUC statistics for the 8-feature model for the classification of amyloid status within each diagnostic group, and APOE ɛ4 carriers and non-carriers

	AUC	Sensitivity	Specificity	LR	N
Whole cohort (AD, MCI, CTL)	0.742	0.682	0.704	2.30	374
MCI	0.743	0.658	0.785	3.06	193
CTL	0.768	0.682	0.776	3.04	142
MCI and CTL combined	0.724	0.677	0.661	2.00	335
APOE ɛ4 non-carriers	0.736	0.681	0.725	2.47	199
APOE ɛ4 carriers	0.836	0.757	0.767	3.25	175

MCI, mild cognitive impairment; AD, Alzheimer’s disease, APOE, apolipoprotein E; CTL, cognitively healthy control; AUC, area under the curve; LR, likelihood ratio.