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. 2020 Mar 10;74(1):213–225. doi: 10.3233/JAD-190434

Table 5.

Linear and logistic regression (age as covariate) results for each protein with alternative outcome measures

Aβ Z-score P-Tau Z-score T-Tau Z-score Hippocampal volume MMSE MCI conversion to dementia
Sample set protein Linear regression Linear regression Linear regression Linear regression Linear regression Logistic regression
β p q β p q β p q β p q β p q β p q
Oxford
FCN2 –0.19 0.000* 0.000* –0.125 0.017* 0.098 –0.138 0.019* 0.132 –244.14 0.000* 0.000* –0.88 0.000* 0.000* –0.398 0.002* 0.006*
B2M –00.125 0.001* 0.001* –0.019 0.715 0.876 –0.001 0.991 0.991 –14.6 0.758 0.758 –0.174 0.183 0.214 –0.039 0.729 0.901
apoE –00.123 0.000* 0.001* –0.05 0.334 0.584 –0.045 0.444 0.778 00–37.388 0.403 0.470 –0.184 0.146 0.204 –0.015 0.901 0.901
A1AT –0.07 0.061 0.061 –0.011 0.843 0.876 –0.006 0.924 0.991 –0172.168 0.000* 0.001* –0.239 0.078 0.181 –0.096 0.520 0.901
CC4 1–0.117 0.001* 0.001* –0.088 0.09 0.209 –0.045 0.445 0.778 00–70.691 0.112 0.261 –0.131 0.306 0.306 –0.153 0.207 0.483
Cathepsin D 0–0.086 0.013* 0.016* –0.008 0.876 0.876 –0.017 0.776 0.991 –0046.917 0.306 0.429 –0.195 0.118 0.204 –0.032 0.792 0.901
Cardiff
CFI 0*0.117 0.001* 0.002* –0.116 0.028* 0.098 –0.107 0.063 0.221 *0052.396 0.256 0.429 –0.442 0.001* 0.002* –0.932 0.000* 0.000*

*Statistically significant < 0.05.