Table 3.
Group differences in seed-based functional connectivity of the insular subregions.
| Seed | Connected regions | L/R | Voxels | BA | MNI coordinates | T | ||
|---|---|---|---|---|---|---|---|---|
| X | Y | Z | ||||||
| R_vAI | Middle temporal gyrus | L | 14 | 39 | −42 | −68 | 27 | −4.66 |
| Angular | R | 7 | 19 | 41 | −66 | 42 | −5.17 | |
| L_dAI | Medial frontal gyrus | L | 12 | 29 | −9 | 54 | −3 | 5.51 |
| R_dAI | Superior temporal gyrus | L | 8 | 31 | −54 | 15 | −9 | 4.19 |
| Precuneus | L | 7 | 6 | −27 | −76 | 39 | −4.88 | |
| R_PI | Lingual gyrus | R | 45 | 6 | 27 | −72 | 3 | −4.41 |
BA, Broadmann area; BD, bipolar disorder; HC, healthy controls; dAI, dorsal anterior insula; AI, ventral anterior insula; PI, posterior insula; MNI, Montreal Neurological Institute.