Table 2. Comparison of first UPSIT score and mean of all UPSIT scores with visual hallucinations and parkinsonism as predictors of ADD/DLB vs ADD.
| Predictor | Sensitivity | Specificity | Accuracy | Odds Ratio (95% CI), p-value | AUC | P-value |
|---|---|---|---|---|---|---|
| First UPSIT1 | 93.1% | 64.6% | 71.2% | 17.5 (5.1, 91.6) < .0001 | 82.9% | 0.24193 |
| Matched Year hallucinations1 | 17.2% | 96.9% | 78.4% | 4.4 (0.9, 25.0) 0.0905 | 67.4% | 0.00124 |
| Matched Year parkinsonism1 | 31.0% | 77.1% | 66.4% | 1.7 (0.7, 4.3) 0.2648 | 67.4% | 0.00064 |
| Mean UPSIT2 | 86.2% | 71.9% | 75.2% | 18.0 (6.0, 66.8) < .0001 | 87.2% | 0.24193 |
| Cumulative hallucinations2 | 51.7% | 76.0% | 70.4% | 3.3 (1.4, 8.4) 0.0106 | 72.9% | 0.0084 |
| Cumulative parkinsonism2 | 65.5% | 45.8% | 50.4% | 1.6 (0.7, 3.9) 0.3001 | 68.2% | 0.00074 |
“Matched” indicates that determinations of the presence or absence of hallucinations and parkinsonism were done close to the same year as the first UPSIT examination.
1. Adjusted for matched year MMSE and age at first UPSIT.
2. Adjusted for mean MMSE and age at death.
3. P-value comparing AUCs for first and mean UPSIT.
4. P-value comparing AUC with first UPSIT.
5. P-value comparing AUC with mean UPSIT.