Skip to main content
. 2020 Apr 22;17(4):e1003095. doi: 10.1371/journal.pmed.1003095

Fig 3. Changes in SUA.

Fig 3

The values are expressed as means, with the error bars showing the SDs. (A) Changes in mean SUA. The mean values of SUA were lower in the febuxostat group at 6 months (febuxostat, 5.14 [SD 1.26] mg/dL versus control, 7.43 [SD 1.14] mg/dL; mean between-group difference [febuxostat − control] −2.28 mg/dL [95% CI −2.50 to −2.06 mg/dL ]; P < 0.001), 12 months (febuxostat: 5.06 [SD 1.32] mg/dL versus control, 7.31 [SD 0.99] mg/dL; mean between-group difference −2.25 mg/dL [95% CI −2.47 to −2.03 mg/dL]; P < 0.001), and 24 months (febuxostat, 4.66 [SD 1.27] mg/dL versus control, 7.28 [SD 1.27] mg/dL; mean between-group difference −2.62 mg/dL [95% CI −2.86 to −2.38 mg/dL]; P < 0.001). (B) Absolute changes in SUA. The mean between-group differences in the absolute change in SUA from baseline were also significant at 6 months (−2.31 mg/dL [95% CI −2.55 to −2.08 mg/dL]; P < 0.001), 12 months (−2.31 mg/dL [95% CI −2.56 to −2.06 mg/dL]; P < 0.001), and 24 months (−2.65 mg/dL [95% CI −2.93 to −2.37 mg/dL]; P < 0.001). CI, confidence interval; SD, standard deviation; SUA, serum uric acid.