Table 3.
Associations Between Age, Sex, and Date of Visit a Medical History With Cortisol Levels: Results From the Reduced Fully Adjusted Model
| Effect | Estimate | SE | P > |t| |
|---|---|---|---|
| Intercept | 22.99 | 0.45 | <.0001 |
| Date of visit (y) (linear) | −0.085 | 0.033 | .011 |
| Date of visit (quadratic) | −0.027 | 0.0025 | <.0001 |
| Age (decades) | 0.26 | 0.16 | .11 |
| Age (quadratic) | 0.20 | 0.072 | .0055 |
| Race (white/nonwhite) | −3.15 | 0.52 | <.0001 |
| High-density lipoprotein (linear) | 0.67 | 0.27 | .014 |
| High-density lipoprotein (quadratic) | −0.24 | 0.094 | .011 |
| Body mass index | −2.30 | 0.22 | <.0001 |
| Current smoker (Y/N) | −2.92 | 0.88 | .0009 |
| Former smoker (Y/N) | −0.99 | 0.44 | .023 |
| Hypertension (Y/N) | −0.87 | 0.42 | .038 |
| Corticosteroid usea (Y/N) | −1.27 | 0.49 | .010 |
| Diruetic use (Y/N) | −5.29 | 0.48 | <.0001 |
| Statin use (Y/N) | −0.93 | 0.41 | .025 |
| High-density lipoprotein × age (linear) | 0.11 | 0.14 | .43 |
| High-density lipoprotein × age (quadratic) | 0.16 | 0.062 | .0096 |
Note: aThe fully adjusted model was recomputed after excluding visits in which corticosteroid use was present. The exclusion of these visits did not substantially alter the findings.