Table 3. Sex-specific associationsa of σ-standardised anthropometric measures with the prevalence of helicobacter pylori and the human herpesviruses 3 to 6, KORA F4 study, 2006–2008.
| Men | Helicobacter pylori n = 1,452 | Varicella-zoster virus n = 1,248 | Epstein-Barr virus n = 1,452 | Cytomegalovirus n = 1,452 | Human herpesvirus 6 n = 1,452 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | E-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Body mass index (kg/m2) | 1.01 (0.90, 1.14) | 0.881 | 1.06 (0.90, 1.24) | 0.505 | 0.81 (0.60, 1.09) | 0.164 | 1.02 (0.92, 1.15) | 0.678 | 1.05 (0.94, 1.18) | 0.392 | |
| Waist-to-hip ratio | 1.09 (0.95, 1.24) | 0.218 | 1.08 (0.90, 1.28) | 0.404 | 0.92 (0.64, 1.32) | 0.650 | 1.08 (0.95, 1.23) | 0.214 | 1.04 (0.91, 1.18) | 0.595 | |
| Waist-to-height ratio | 1.07 (0.94, 1.22) | 0.307 | 1.05 (0.88, 1.25) | 0.579 | 0.84 (0.59, 1.19) | 0.316 | 1.08 (0.96, 1.23) | 0.198 | 1.02 (0.90, 1.15) | 0.811 | |
| Waist circumference (cm) | 1.01 (0.90, 1.15) | 0.841 | 1.03 (0.88, 1.21) | 0.704 | 0.89 (0.64, 1.23) | 0.469 | 1.02 (0.91, 1.15) | 0.715 | 1.06 (0.94, 1.19) | 0.347 | |
| Body adiposity index | 1.07 (0.94, 1.21) | 0.306 | 1.03 (0.87, 1.21) | 0.769 | 0.80 (0.57, 1.11) | 0.185 | 1.09 (0.97, 1.23) | 0.158 | 0.97 (0.86, 1.09) | 0.573 | |
| Women | n = 1,556 | n = 1,313 | n = 1,556 | n = 1,556 | n = 1,556 | ||||||
| Body mass index (kg/m2) | 1.04 (0.92, 1.17) | 0.525 | 1.17 (1.02, 1.35) | 0.027 | 1.62 | age-interactiona | 0.043 | 1.07 (0.96, 1.20) | 0.222 | non-linearb | 0.063 |
| Waist-to-hip ratio | 1.06 (0.94, 1.21) | 0.333 | 1.12 (0.97, 1.29) | 0.115 | 0.74 (0.44, 1.23) | 0.246 | 1.08 (0.96, 1.21) | 0.194 | 1.02 (0.91, 1.15) | 0.689 | |
| Waist-to-height ratio | 1.06 (0.93, 1.21) | 0.366 | 1.22 (1.05, 1.42) | 0.010 | 1.73 | 0.65 (0.39, 1.07) | 0.089 | 1.09 (0.96, 1.23) | 0.185 | non-linearb | 0.132 |
| Waist circumference (cm) | 1.06 (0.93, 1.20) | 0.380 | 1.22 (1.06, 1.41) | 0.007 | 1.73 | age-interactiona | 0.014 | 1.09 (0.97, 1.22) | 0.137 | 1.06 (0.95, 1.18) | 0.319 |
| Body adiposity index | 1.04 (0.92, 1.19) | 0.513 | 1.17 (1.01, 1.36) | 0.032 | 1.63 | 0.73 (0.45, 1.19) | 0.210 | 1.05 (0.93, 1.18) | 0.459 | non-linearb | 0.069 |
Abbrevations: CI, confidence interval; OR, odds ratio.
a Multivariable binary logistic regression models were adjusted for age, years of education, rooted alcohol consumption, physical activity, smoking and drinking status. E-values of point estimates are presented for significant linear associations (bold).
b Body adiposity index = (hip circumference in cm / height in m3/2) - 18.
c Exposure-age-interactions are illustrated in Fig 3.
d Non-linear associations are illustrated in Fig 4.