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. 2013:493–532. doi: 10.1007/978-3-642-17907-5_23

Fig. 23.14.

Fig. 23.14

Fig. 23.14

Elastase inhibitors 23.21 and 23.22 (ICI 200880) are substrate analogues. Compound 23.22 is a highly active compound, but it is not orally available.