Figure 5. Change from baseline in blood lactate during submaximal exercise with 12 weeks omaveloxolone treatment.

Change in blood lactate (A) at the end of and (B) during 30 minutes of submaximal exercise on a recumbent cycle ergometer in patients with mitochondrial myopathy with 12 weeks of treatment with placebo and 160 mg omaveloxolone (Omav) vs baseline (BL). Presented are mean values with SE bars.