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. Author manuscript; available in PMC: 2021 Feb 11.
Published in final edited form as: Vaccine. 2020 Jan 17;38(7):1652–1660. doi: 10.1016/j.vaccine.2019.12.062

Figure 3.

Figure 3.

Characterization of process and storage loss of IPV D-antigens in silk fibroin films after storage at 45°C. Formulation development for IPV in silk fibroin films required initial assessment of loss through air-drying (A, type 1 ELISA; dashed line represents recovery from dried IPV alone without silk) and losses during storage at 45°C for one month for (B) type 1, (C) type 2, and (D) type 3 poliovirus strains. After running a mid-point ELISA for recovery, certain groups were abandoned for analysis at day 28. Displayed are average DU recovery values compared to theoretical loading (n=3 films) with standard deviation. Formulations are described in Supplemental Fig. 2.