Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 20;133(8):919–928. doi: 10.1097/CM9.0000000000000742

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0

PMC Copyright notice

SiRNA-mediated inhibition of KIF22. (A) The expression of KIF22 in six GC cell lines was examined by Western blotting compared with one non-tumorigenic cell line. (B) KIF22 knockdown efficiencies were determined by Western blotting. (C) MTT assays displays decreased proliferation in MGC-803 after using KIF22 siRNA. (D) MTT assays display decreased proliferation in BGC-823 after using KIF22 siRNA. (E) Suppression of KIF22 decreased the colony formation ability of MGC-803 and BGC-823 cells. ∗P < 0.05 and ⁺P < 0.01 for the SiRNA1 group vs. the control group, respectively. SiRNA: Small interfering RNA; KIF22: Kinesin superfamily protein 22; MTT: 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide.